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KMID : 1134820130420040556
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Journal of the Korean Society of Food Science and Nutrition
2013 Volume.42 No. 4 p.556 ~ p.562
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Effects of Water-Soluble Polysaccharides from Tott on Lipid Absorption and Animal Body Weight
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Baek Gu
Koo Bon-Geun
Ahn Byung-Jae
Park Jae-Kweon
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Abstract
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We examined the anti-obesity effects of water-soluble polysaccharides (WSP-A) extracted from the seaweed Hijikia fusiforme (Tott in Korean). The extracted alginate-like polysaccharide (verified by FT-IR and HPAEC- PAD analysis) was examined in a lipase inhibition assay and animal experiments. WSP-A inhibited lipase up to 30%, with over 80% of the initial activity retained until the 1 hour reaction in vitro. There was a 30% loss in the rate of weight gain in rats fed a high-fat diet. WSP-A therefore seems to serve as a healthy weight loss agent by inhibiting lipases, thus preventing the absorption of fat in the body.
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KEYWORD
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seaweed, Tott (Hijikia fusiforme), polysaccharides, anti-obesity, lipase inhibitor
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